{"product_id":"hialurom-forte-1-x-2-ml","title":"Hialurom Forte 1x 2.0 ml","description":"\u003cp\u003e\u003ca href=\"https:\/\/stakonmed.de\/collections\/hialurom\" title=\"Hialurom | Gelenkspritzen | StakonMed\"\u003eHIALUROM\u003c\/a\u003e\u003c\/p\u003e\n\u003cp\u003eSodium hyaluronate 30 mg 2 ml, sterile solution for injection in a prefilled syringe\u003c\/p\u003e\n\u003cp\u003eFor intraarticular injection\u003c\/p\u003e\n\u003cp\u003eDESCRIPTION:\u003c\/p\u003e\n\u003cp\u003eHialurom is a sterile, viscoelastic solution of sodium hyaluronate. Hialurom contains 30 mg in 2 ml of sterile sodium hyaluronate with a molecular weight of 1.5 - 2.4 million Daltons, dissolved in physiological saline with an average osmolarity of 335 milliosmols, in a prefilled syringe. The sodium hyaluronate is obtained by bacterial fermentation of a Streptococcus strain and subsequently purified.\u003c\/p\u003e\n\u003cp\u003eEach milliliter of Hialurom contains 15 mg sodium hyaluronate, sodium chloride, and water for injection.\u003c\/p\u003e\n\u003cp\u003eSterile by moist heat.\u003c\/p\u003e\n\u003cp\u003eINDICATIONS:\u003c\/p\u003e\n\u003cp\u003eHialurom is indicated as a viscoelastic supplement or replacement of synovial fluid in the human knee joint.\u003c\/p\u003e\n\u003cp\u003eHialurom is indicated for the symptomatic treatment of knee osteoarthritis. Hialurom acts as a lubricant and mechanical support.\u003c\/p\u003e\n\u003cp\u003eCONTRAINDICATIONS:\u003c\/p\u003e\n\u003cp\u003eThe following pre-existing conditions may represent relative or absolute contraindications for the use of Hialurom:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eallergies (hypersensitivity) to any of the components of Hialurom,\u003c\/li\u003e\n\u003cli\u003eexisting skin infections at the injection site,\u003c\/li\u003e\n\u003cli\u003eknown infection in the index finger joint,\u003c\/li\u003e\n\u003cli\u003eknown systemic bleeding disorders.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eHialurom may contain traces of proteins from gram-positive bacteria and is contraindicated for patients with known allergies of this type.\u003c\/p\u003e\n\u003cp\u003ePOSSIBLE SIDE EFFECTS:\u003c\/p\u003e\n\u003cp\u003eSodium hyaluronate is a natural component of human tissue. Since sodium hyaluronate is classified as non-inflammatory, all inflammatory reactions are attributed to the injection procedure itself. Occasionally, mild to moderate temporary swelling and discomfort have been observed after intraarticular injection of sodium hyaluronate preparations. There are minimal risks associated with the injection procedure, primarily infections and bleeding.\u003c\/p\u003e\n\u003cp\u003eADMINISTRATION AND DOSAGE:\u003c\/p\u003e\n\u003cp\u003eHialurom may only be administered by medical professionals trained in intraarticular injection techniques.\u003c\/p\u003e\n\u003cp\u003eHialurom may only be administered intraarticularly.\u003c\/p\u003e\n\u003cp\u003eIt must not be administered intravenously.\u003c\/p\u003e\n\u003cp\u003eStrict aseptic administration techniques must be followed.\u003c\/p\u003e\n\u003cp\u003eThe injection site must be properly disinfected (70% alcohol or another disinfectant). Disinfectants containing quaternary ammonium salts should not be used for skin disinfection, as this may cause a failure reaction of the hyaluronic acid. Hialurom is administered once weekly into the affected joint over three consecutive weeks. For bilateral treatment, a separate syringe should be used for each knee. Each joint may only undergo one treatment cycle within a 6-month period.\u003c\/p\u003e\n\u003cp\u003eAny joint effusion must be removed by joint aspiration before injecting Hialurom. The joint space must not be overfilled. Hialurom is available as a prefilled syringe and must not be diluted. The contents of the Hialurom prefilled syringe are sterile and must be used immediately once the package is opened. Hialurom must be slowly injected into the joint space using a standard intra-articular injection technique.\u003c\/p\u003e\n\u003cp\u003eRemove the prefilled syringe from the packaging. Break the visible seal before use and remove the cap from the prefilled syringe. Attach the hypodermic needle of a suitable size (gauge) and length (inch) and ensure it is properly secured by gently twisting. Prime the syringe before injection.\u003c\/p\u003e\n\u003cp\u003eCommon needle sizes for injections into the knee are between 18 and 21 G (1.2-0.8 mm).\u003c\/p\u003e\n\u003cp\u003eThe final choice of needle for each treatment is made by the doctor,\u003c\/p\u003e\n\u003cp\u003ePRECAUTIONS:\u003c\/p\u003e\n\u003cp\u003eGeneral precautions for intraarticular injections must be observed. Hialurom must only be injected into the joint space by trained medical personnel. If pain increases during the injection, the injection must be stopped and the needle withdrawn.\u003c\/p\u003e\n\u003cp\u003ePatients must be carefully examined for signs of acute inflammation before administration, and the doctor must decide whether treatment with Hialurom should be started in such cases.\u003c\/p\u003e\n\u003cp\u003eAs with any invasive joint procedure, it is recommended not to overload the joint immediately after the intraarticular injection.\u003c\/p\u003e\n\u003cp\u003ePatients who experience abnormal follow-up complications after administration of Hialurom must see a doctor immediately. There is insufficient data to recommend use in children and adolescents, pregnant and breastfeeding women. Hialurom must not be administered simultaneously or mixed intraarticularly with other products.\u003c\/p\u003e\n\u003cp\u003eWARNINGS:\u003c\/p\u003e\n\u003cp\u003eThe product Hialurom is intended for single use!\u003c\/p\u003e\n\u003cp\u003eDo not reuse.\u003c\/p\u003e\n\u003cp\u003eEach Hialurom prefilled syringe is intended for use on a single patient only.\u003c\/p\u003e\n\u003cp\u003eDo not use the syringe if the seal is opened or damaged.\u003c\/p\u003e\n\u003cp\u003eThe product must not be re-sterilized as this may damage or alter the product.\u003c\/p\u003e\n\u003cp\u003eThe product should only be used if the solution is clear.\u003c\/p\u003e\n\u003cp\u003eUsed needles and syringes must be disposed of after each injection and must not be kept for other administrations.\u003c\/p\u003e\n\u003cp\u003eReusing already used needles and syringes can lead to the transmission of infectious agents (including HIV and hepatitis).\u003c\/p\u003e\n\u003cp\u003eHialurom should be brought to room temperature before use by storing it, if necessary, for about 20-45 minutes at appropriate temperatures before administration.\u003c\/p\u003e\n\u003cp\u003eKeep out of reach of children.\u003c\/p\u003e\n\u003cp\u003eDo not use after the expiration date on the label.\u003c\/p\u003e\n\u003cp\u003ePROPERTIES AND MODE OF ACTION:\u003c\/p\u003e\n\u003cp\u003eThe sodium hyaluronate in Hialurom is a polysaccharide consisting of sodium glucuronate and N-acetylglucosamine.\u003c\/p\u003e\n\u003cp\u003eSodium hyaluronate is ubiquitous in human tissue and is found in high concentrations in certain tissues such as the vitreous body, synovial fluid, umbilical cord, and dermis. In synovial joints, sodium hyaluronate acts as a lubricant and shock absorber, enabling normal movements without joint pain. In degenerative joint diseases (osteoarthritis), the viscoelasticity of synovial fluid is impaired, which greatly increases mechanical stress on the joint and destruction of joint cartilage, leading to restricted and painful joint movement.\u003c\/p\u003e\n\u003cp\u003eThe lubricating and shock-absorbing properties of sodium hyaluronate reduce pain and improve joint mobility when administered intra-articularly.\u003c\/p\u003e\n\u003cp\u003eThis effect can last for 6 months after a treatment cycle of 1-3 intra-articular injections.\u003c\/p\u003e\n\u003cp\u003eViscosupplementation with hyaluronic acid is an effective and well-tolerated therapy for knee osteoarthritis. Viscosupplementation is also a well-tolerated therapy for osteoarthritis of other joints, but a consensus on the effectiveness of viscosupplementation with hyaluronic acid for other joint osteoarthritis has not yet been reached worldwide.\u003c\/p\u003e\n\u003cp\u003eCOMPOSITION:\u003c\/p\u003e\n\u003cp\u003eEach milliliter of Hialurom contains 15 mg sodium hyaluronate, 9 mg sodium chloride, and water for injection. Each syringe contains 2 ml of sterile, viscoelastic solution of 30 mg sodium hyaluronate. Hialurom is available in a carton box with the following contents:\u003c\/p\u003e\n\u003cp\u003e- one blister with a disposable prefilled syringe and instructions for use,\u003c\/p\u003e\n\u003cp\u003e- three blisters with disposable prefilled syringes and instructions for use.\u003c\/p\u003e\n\u003cp\u003eSTORAGE:\u003c\/p\u003e\n\u003cp\u003eThe product should be stored in its original packaging. The storage temperature should not exceed 25°C. Do not freeze.\u003c\/p\u003e\n\u003cp\u003eInformation status: February 2019\u003c\/p\u003e","brand":"actrevo GmbH","offers":[{"title":"Default Title","offer_id":47355879489876,"sku":"113","price":29.95,"currency_code":"EUR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0786\/8756\/8212\/files\/hialurom-forte-actrevo-gmbh-gelenkspritzen-stakonmed-243872.jpg?v=1772214439","url":"https:\/\/stakonmed.de\/en\/products\/hialurom-forte-1-x-2-ml","provider":"StakonMed","version":"1.0","type":"link"}